Effects produced by trypsin on certain properties of the human red cell.

ponents of the i-ed cell surface, lead one to ask whether this is an isolated phenomenon omwhether tmypsinization affects red cells in other ways. This question is of additional interest because there is no known instance in which the more general l)ioperties of the i-ed cell surface are affected! by proteolytic enzymes (cf. Ballantine and Parpart,2 who found that trypsin produces no effect on permeabihity). It can be answeie(! by examining a variety of properties associated with the normal ied cell and seeing how these are affected by trypsin and the related enzyme mexacain, a papain-like enzyme for which no activator is required. This